Thyroid Peroxidase (TPO) (N-Term) Peptide
TPO
Reactivité: Humain
Hôte: Synthetic
BP, WB
N° du produit ABIN5511606
Aperçu rapide pour Thyroid Peroxidase (TPO) (N-Term) Peptide (ABIN5511606)
Antigène
Thyroperoxidase (TPO)
(Thyroid Peroxidase (TPO))
Origine
Humain
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- N-Term
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Séquence
- GASNTALARW LPPVYEDGFS QPRGWNPGFL YNGFPLPPVR EVTRHVIQVS
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Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-TPO Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Stock
- -20 °C
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Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Thyroperoxidase (TPO) (Thyroid Peroxidase (TPO))
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Sujet
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This gene encodes a membrane-bound glycoprotein. The encoded protein acts as an enzyme and plays a central role in thyroid gland function. The protein functions in the iodination of tyrosine residues in thyroglobulin and phenoxy-ester formation between pairs of iodinated tyrosines to generate the thyroid hormones, thyroxine and triiodothyronine. Mutations in this gene are associated with several disorders of thyroid hormonogenesis, including congenital hypothyroidism, congenital goiter, and thyroid hormone organification defect IIA. Multiple transcript variants encoding distinct isoforms have been identified for this gene, but the full-length nature of some variants has not been determined.
Protein Size: 611 -
ID gène
- 7173
Antigène
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